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. 2014 Dec 15;38(6):426–436. doi: 10.4093/dmj.2014.38.6.426

Table 1.

Therapeutic approaches for maintaining β-cell function and mass in animal and human data

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PPARγ, peroxisome proliferator-activated receptor-gamma; GLUT2, glucose transporter 2; ADOPT, A Diabetes Outcome Progression Trial; ACT NOW, Actos Now for Prevention of Diabetes; PIPOD, Pioglitazone In Prevention Of Diabetes; TRIPOD, TRoglitazone In the Prevention Of Diabetes; GLP-1, glucagon-like peptide-1; ER, endoplasmic reticulum; DPP-4, dipeptidyl peptidase-4; GSK3β, glycogen synthase kinase 3 β; GPR40, G protein-coupled receptor 40.