Table 1.
Clinicopathologic factors in clinically node-negative breast cancer patients undergoing SLN biopsy at a single institution
| Clinicopathologic factor | [99mTc]Tilmanocept (N = 84) n (%) | fTcSc (N = 115) n (%) | P value |
|---|---|---|---|
| Age | Mean 57.2 ± 10.8 | Mean 59.7 ± 11.2 | 0.11 |
| Tumor size | 0.13 | ||
| T1 | 61 (73) | 74 (64) | |
| T2 | 22 (11) | 33 (29) | |
| T3 | 1 (5) | 8 (7) | |
| Tumor histology | 0.47 | ||
| IDC | 48 (57) | 72 (63) | |
| ILC | 11 (13) | 9 (8) | |
| Mixed (IDC + ILC)/other | 25 (30) | 34 (29) | |
| ER status | 0.52 | ||
| Positive | 75 (89) | 98 (85) | |
| Negative | 9 (11) | 17 (15) | |
| PR status | 0.18 | ||
| Positive | 68 (81) | 83 (72) | |
| Negative | 16 (19) | 32 (28) | |
| Her-2neu status | 0.85 | ||
| Amplified | 14 (17) | 18 (16) | |
| Unamplified | 70 (83) | 97 (84) | |
| Triple negative | 0.22 | ||
| Yes | 5 (6) | 14 (12) | |
| No | 79 (94) | 101 (88) | |
| Tumor grade (MBR) | 0.25 | ||
| 1 | 32 (38) | 42 (35) | |
| 2 | 28 (33) | 50 (43) | |
| 3 | 24 (29) | 23 (20) | |
| LVI | 0.73 | ||
| Present | 17 (20) | 26 (23) | |
| Absent | 67 (80) | 89(77) | |
| Surgery | 0.33 | ||
| Lumpectomy | 66 (79) | 83 (72) | |
| Mastectomy | 18 (21) | 32(28) | |
fTcSc filtered-[99mTc] sulfur colloid, IDC invasive ductal carcinoma, ILC invasive lobular carcinoma, MBR Modified-Bloom Richardson score, LVI lymphovascular invasion