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. 2014 Dec 21;20(47):17863–17876. doi: 10.3748/wjg.v20.i47.17863

Table 1.

Genes that displayed the greatest changes in their expressions in the claudin 1 small interfering RNA transfected MKN28 cells

Gene symbol Gene ID Gene name Fold change
Up-regulated genes
FGF6 NM_020996 Fibroblast growth factor 6 151.34
TM4SF20 NM_024795 Transmembrane 4 L six family member 20 72.03
B4GALNT2 NM_153446 Beta-1,4-N-acetyl-galactosaminyl transferase 2 47.30
SLC2A13 BC047507 Solute carrier family 2 (facilitated glucose transporter), member 13 43.02
HS3ST2 NM_006043 Heparan sulfate (glucosamine) 3-O-sulfotransferase 2 28.39
ZNF596 NM_001042416 Zinc finger protein 596 26.36
IL2RA NM_000417 Interleukin 2 receptor, alpha 22.00
CCL2 NM_002982 Chemokine (C-C motif) ligand 2 18.05
SGOL2 BC048349 Shugoshin-like 2 17.64
SYT4 NM_020783 Synaptotagmin IV 17.29
FGF19 NM_005117 Fibroblast growth factor 19 16.44
ARID5B NM_032199 AT rich interactive domain 5B 14.47
DEFB105B NM_001040703 Defensin, beta 105B 14.34
DSG3 NM_001944 Desmoglein 3 12.99
RSPH1 NM_080860 Radial spoke head 1 homolog (Chlamydomonas) 12.82
COL5A2 NM_000393 Collagen, type V, alpha 2 12.72
NRG2 NM_013982 Neuregulin 2 12.63
TMEM26 NM_178505 Transmembrane protein 26 12.22
CCL3L3 NM_001001437 Chemokine (C-C motif) ligand 3-like 3 11.54
OR51E1 NM_152430 Olfactory receptor, family 51, subfamily E, member 1 9.43
Down-regulated genes
LY6G6F NM_001003693 Lymphocyte antigen 6 complex, locus G6F -332.04
WT1 NM_024426 Wilms tumor 1 -68.28
MADCAM1 NM_130760 Mucosal vascular addressin cell adhesion molecule 1 -60.84
SLC2A9 NM_001001290 Solute carrier family 2 (facilitated glucose transporter), member 9 -48.05
SULT4A1 NM_014351 Sulfotransferase family 4A, member 1 -39.30
SYNPR NM_144642 Synaptoporin -36.73
C10orf47 NM_153256 Chromosome 10 open reading frame 47 -29.96
MAS1L NM_052967 MAS1 oncogene-like -29.67
CLDN1 NM_021101 Claudin 1 -26.87
CBX1 NM_006807 Chromobox homolog 1 -26.37
MPPED2 NM_001145399 Metallophosphoesterase domain containing 2 -25.00
SCUBE2 NM_020974 Signal peptide, CUB domain, EGF-like 2 -22.13
CHI3L2 NM_001025199 Chitinase 3-like 2 -21.67
SLIT2 NM_004787 Slit homolog 2 -21.60
HFM1 NM_001017975 HFM1, ATP-dependent DNA helicase homolog -20.56
CR1 NM_000651 Complement component (3b/4b) receptor 1 -18.04
PLA2G10 NM_003561 Phospholipase A2, group X -16.70
GRIP2 NM_001080423 Glutamate receptor interacting protein 2 -16.45
XIST NR_001564 X (inactive)-specific transcript -15.79
TNF-SF10 NM_003810 Tumor necrosis factor (ligand) superfamily, member 10 -15.26