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. 2014 Dec 21;20(47):17894–17904. doi: 10.3748/wjg.v20.i47.17894

Figure 5.

Figure 5

Knockdown of VE-cadherin inhibits proliferation and promotes apoptosis of esophageal squamous cell carcinoma cells. A: shRNA-mediated VE-cadherin knockdown inhibits the proliferation of ESCC cells. Eca109, TE13 and their derived stable cells were cultured under normoxic conditions and proliferation was determined by MTT assay; aP < 0.05; B: shRNA-mediated VE-cadherin knockdown promoted apoptosis of ESCC cells. Eca109, TE13 and their derived stable cells were cultured under normoxic or hypoxic conditions and apoptosis was detected by Annexin V staining. ESCC: Esophageal squamous cell carcinoma.