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p38 inhibitor decreases the expression of interleukin-8. When p38 inhibitor was used, the interleukin (IL)-8 expression levels declined in all three groups. IL-17 + TNF-α vs S + IL-17 + TNF-α, t = 103.701, P = 0.000; S + IL-17 + TNF-α vs S + TNF-α, t = - 4.131, P = 0.07; S + IL-17 + TNF-α vs S + IL-17, t = -11.509, P = 0.000. IL-8: Interleukin-8; TNF-α: Tumor necrosis factor-α; S: SB203580.
