FIG. 4.

Density of BrdU-positive cells in the subgranular zone (SGZ) after treatment with vehicle versus CBSC (A–C). A nonsignificant (P=0.065) increase was noted in density on the contralateral side of injured animals (A-right). However, when broken down by animal sex (B) this increase was significant and seen only in males ipsilaterally, P<0.05 (B-left). (C) Rostro-caudal analyses by hippocampal section along the AP axis revealed a significant sex difference by Poisson regression (see text, page 6, column 2) in CBSC-treated versus vehicle-treated injured littermates. The upregulation of SGZ proliferation was driven by CBSC-treated males within the data set. (*P<0.05).