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. 2014 Nov 7;10:2603–2622. doi: 10.3762/bjoc.10.273

Table 2.

List of active molecules used in biocidal formulations (in bold: active biocides mentioned in this review) and their mode of action classified on the basis of active chemical groups.a

Active chemical groups Active molecules General mode of action

Alcohols Ethanol
Benzyl alcohol
Inhibition of DNA and RNA synthesis
Aldehydes Glutaraldehyde
Formaldehyde
Alkylating agents
Amphiphiles Didecyldimethyammonium chloride
Benzalkonium chloride
Membrane destabilizer, cytoplasmic protein aggregation
Azole derivatives Enilconazole
Miconazole
Tebuconazole
Inhibition of the ergosterol synthesis, interaction with DNA
Biguanides Chlorhexidine Inhibition of membrane-bound adenosine triphosphatase (ATPase)
Carbamates Bendiocarb
Carbendazim
Carbofuran
Inactivation of the acetylcholinesterase
Halogens Chlorine
Iodine
Oxidizing agents
Heavy-metal derivates Copper
Silver
Interaction with thiol residues
Neonicotinoids Imidacloprid
Sulfoxaflor
Binding to nicotinic acetylcholine receptors
Organic acids Lactic acid
p-Hydroxybenzoic acid ester
Butylparaben
Dissipation of proton motive force and inhibition of uptake amino acids
Organophosphates Chloramidophos
DCPE
Inactivation of the acetylcholinesterase
Phenol, Bisphenol and derivatives m-Cresol
Pentachlorophenol
Triclosan
Inhibition of uptake amino acids, modification of membrane potential
Pyrethroids Allethrin
Cypermethrin
Modification of membrane potential
Quinolones Ciprofloxacin
Levofloxacin
Inhibition of the topoisomerase
Terpenes Limonene
trans-cinnamaldehyde
Eugenol
Unknown membrane interaction

aNote that the list is not exhaustive. The reader can consult reference [15] for more details.