Table 2.

Parameters describing the adsorption of HSA and chemically modified HSA onto NPs with different surface coatings.

NP/surface charge		RH (nm)	Protein	ΔRH (nm)	K′D (µM)	n
Cysteamine–QD	+	6.3 ± 0.4	HSA	4.4 ± 0.4	0.025 ± 0.007	1.5 ± 0.4
DPA–QD	—	6.1 ± 0.1	HSA	2.8 ± 0.2	0.31 ± 0.06	1.0 ± 0.2
QD ITK 585	—	9.3 ± 0.2	HSA	3.2 ± 0.7	24.8 ± 3.8	0.8 ± 0.1
QD ITK 585a	—	7.9 ± 0.3	HSA	3.2 ± 0.4	37 ± 12	0.8 ± 0.2
Polymer–Fe–Pta	—	5.6 ± 0.2	HSA	3.3 ± 0.3	5.1 ± 1.3	0.7 ± 0.1
Polymer–Fe–Ptb	—	6.0 ± 0.1	HSA	3.3 ± 0.3	9.9 ± 4.7	0.9 ± 0.2
DHLA–QDc	—	4.8 ± 0.2	HSA	3.2 ± 0.8	6 ± 3	0.7 ± 0.1
DHLA–QDc	—	4.8 ± 0.2	HSAsuc	8.1 ± 0.6	19 ± 8	0.5 ± 0.1
DHLA–QDc	—	5.6 ± 0.1	HSAam	4.0 ± 0.1	0.022 ± 0.003	1.2 ± 0.1
DHLA–Aud	—	2.9 ± 0.1	HSA	nd	0.08 ± 0.02	0.8 ± 0.1
DHLA–Aud	—	4.0 ± 0.4	HSAsuc	nd	1.2 ± 0.4	0.7 ± 0.1
DHLA–Aud	—	3.5 ± 0.2	HSAam	nd	0.034 ± 0.008	0.7 ± 0.1
DHLA–Age	—	1.1 ± 0.2	HSA	nd	0.37 ± 0.02	nd

Data taken from ^a [45], ^b [46], ^c [22], ^d [49] and ^e [32]. nd = not determined.