Fig. 4.

Free energy barrier for nucleation from solution. (A) For constant interpeptide interaction and various peptide concentrations, ${\mathit{ϵ}}_{ss}=4kT$, and all peptide concentrations are expressed in mM. (B) For various interpeptide interactions (expressed in kT) and constant peptide concentrations, $c=0.72\hspace{0.17em}\text{mM}$. In all cases, ${\mathit{ϵ}}_{s\beta }={\mathit{ϵ}}_{ss}+1kT$. Arrows indicate critical nucleus sizes for several chosen parameters.