Table 4.
Complete list of the NF-κB signaling pathway and associated genes (22 total) considered in this study
Gene | Gene | ||
---|---|---|---|
01 | CHUK † | 12 | NFKB1 † |
02 | FADD | 13 | NFKBIA † |
03 | IKBKB | 14 | RIPK1 † |
04 | IKBKG | 15 | TRAF6 |
05 | IL1R1 | 16 | TRADD † |
06 | IL1A | 17 | TLR4 |
07 | IRAK1 | 18 | TNF |
08 | MAP3K14 † | 19 | TNFRSF1A |
09 | MAP3K7 † | 20 | TNFRSF1B |
10 | TAB1 | 21 | TNFAIP3 |
11 | MYD88 | 22 | RELA † |
Despite the fact that 8 out of these 22 genes denoted by a dagger (†) were shared by the MAPK pathway list in Table 1 (~36% overlap), our stepwise-CCA method failed to identify any statistically significant NF-κB gene clusters for any of the three exposure paradigms.