Table 4.
TAP1-D637G and PSMB9-R60H genotype distribution and allelic frequencies for active versus stable vitiligo phenotypes.
| Phenotype | Number of cases (%) | TAP1-D637G genotypesa | Alleles | PSMB9-R60H genotypes | Allele | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| n (%) | n (frequency) | n (%) | n (frequency) | ||||||||
| DD | DG | GG | D | G | RR | RH | HH | R | H | ||
| Active | 52 (60.5) | 0 (0.0) | 33 (63.5) | 19 (36.5) | 33 (0.32) | 71 (0.68) | 9 (17.3) | 33 (63.5) | 10 (19.2) | 51 (0.49) | 53 (0.51) |
| Stable | 34 (39.5) | 0 (0.0) | 10 (29.4) | 24 (70.6) | 10 (0.15) | 58 (0.85) | 5 (14.7) | 24 (70.6) | 5 (14.7) | 34 (0.50) | 34 (0.50) |
|
| |||||||||||
| OR = 0.66, 95% (CI, 0.01–33.9), | OR = 2.70, 95% (CI, 1.2–5.9), | OR = 1.2, 95% (CI, 0.4–4.0), | OR = 1.0, 95% (CI, 0.5–1.8), | ||||||||
| z = 0.21, P = 0.83a | z = 2.5, P = 0.01b | z = 0.3, P = 0.75c | z = 0.1, P = 0.90b | ||||||||
CI: confidence interval; OR: odds ratio.
a TAP1-D637G genotype differences between progressive and stable vitiligo cases.
b P > 0.05 = no significant difference.
c P < 0.05 = a significant difference.