Table 1. Data with prognostic value for mortality.
Mortality | |||||||
---|---|---|---|---|---|---|---|
short term (in hospital) | long term (after discharge) | ||||||
yes(% exitus)/no(% exitus) | X2c | p | OR (CI 95%) | log rank | p | HR (CI 95%) | |
Age ≥ 80 years | 125 (16%)/185 (11.4%) | 1.03 | 0.310 | 6.98 | 0.008 | 1.77(1.15–2.72) | |
Coronary disease | 67 (16.4%)/243 (12.3%) | 0.44 | 0.504 | 0.91 | 0.340 | ||
Stroke | 59 (15.3%)/251 (12.7%) | 0.09 | 0.766 | 0.59 | 0.444 | ||
Peripheral arteriopathy | 73 (15.1%)/237 (12.7%) | 0.11 | 0.738 | 2.26 | 0.133 | ||
BMI < 25 Kg/m2 | 103 (14.6%)/183 (11.9%) | 0.33 | 0.569 | 9.11 | 0.003 | 2.01(1.27–3.19) | |
SNS > 2 | 198 (16.2%)/112(8%) | 4.10 | 0.043 | 2.21(1.01–4.81) | 11.0 | 0.001 | 2.29(1.38–3.78) |
SNS (M) > 1 | 202 (16.3%)/108 (7.4%) | 4.14 | 0.042 | 2.43(1.08–5.50) | 14.5 | <0.001 | 2.61(1.57–4.36) |
MAC < percentile 10 | 111 (16.2%)/198 (11.6%) | 0.94 | 0.330 | 4.77 | 0.029 | 1.61(1.05–2.49) | |
MAMA < percentile 10 | 147 (17%)/162 (9.9%) | 2.81 | 0.093 | 5.18 | 0.023 | 1.64(1.07–2.53) | |
TSF < percentile 10 | 16 (12.5%)/293 (13.3%) | 0.00 | 1.000 | 4.03 | 0.045 | 2.17(0.99–4.73) | |
Weight loss > 5% | 188 (16.5%)/122 (8.2%) | 4.42 | 0.036 | 2.21(1.04–4.70) | 0.91 | 0.341 | |
Anorexia | 73 (21.9%)/237 (10.5%) | 5.33 | 0.021 | 2.38(1.19–4.76) | 4.46 | 0.035 | 1.68(1.03–2.74) |
Cholesterol < 100 mg/dl | 29 (31%)/275 (10.5%) | 8.28 | 0.004 | 3.82(1.59–9.17) | 5.46 | 0.020 | 2.04(1.11–3.76) |
High stress (disease) | 50 (28%)/260 (10.4%) | 9.86 | 0.002 | 3.36(1.61–6.99) | 5.52 | 0.019 | 1.90(1.10–3.29) |
Serum albumin < 3 g/dl | 86 (23.3%)/220 (8.6%) | 10.6 | 0.001 | 3.21(1.62–6.37) | 5.96 | 0.015 | 1.75(1.11–2.75) |
CRP > 90 mg/dl | 58 (24.1%)/252 (10.7%) | 6.28 | 0.012 | 2.65(1.28–5.46) | 2.75 | 0.098 | |
a1antytrypsin > 250 mg/dl | 46 (17.8%)/143 (11.9%) | 0.58 | 0.446 | 4.94 | 0.026 | 2.57(1.08–6.09) | |
Handgrip < pctil33° | 104 (23.1%)/206 (8.3%) | 12.0 | 0.001 | 3.34(1.70–6.55) | 12.9 | <0.001 | 2.20(1.41–3.42) |
Inability to climb stairs | 140 (18.6%)/170 (8.8%) | 5.54 | 0.019 | 2.36(1.19–4.65) | 10.57 | 0.001 | 2.06(1.34–3.20) |
Inability to walk at discharge | 33.0 | <0.001 | 3.31(2.15–5.10) | ||||
6MWT Inability | 135 (22.2%)/175 (6.3%) | 15.5 | <0.001 | 4.26(2.05–8.87) | 25.7 | <0.001 | 2.95(1.90–4.57) |
ABI < 0.5 | 36 (27.8%)/264 (11%) | 6.48 | 0.011 | 3.11(1.37–7.10) | 10.6 | 0.001 | 2.81(1.47–5.37) |
Cancer | 39 (28.2%)/271 (11.1%) | 7.29 | 0.007 | 3.16(1.43–6.98) | 20.0 | <0.001 | 3.24(1.88–5.60) |
Sepsis | 134 (20.1%)/176 (8%) | 8.82 | 0.002 | 2.92(1.46–5.82) | 0.58 | 0.445 | |
Dementia | 39 (28.2%)/271 (11.1%) | 7.29 | 0.007 | 3.16(1.43–6.98) | 15.9 | <0.001 | 2.77(1.64–4.66) |
Creatinine ≥ 1.2 mg/dl | 130 817.7%)/179 (9.5%) | 4.47 | 0.034 | 2.05(1.04–4.02) | 5.35 | 0.021 | 1.65(1.08–2.54) |
Charlson > 5 | 116 (19.0%)/194 (9.8%) | 4.55 | 0.033 | 2.16(4.18–1.11) | 10.1 | 0.001 | 1.98(1.29–3.03) |
BMI: Body Mass Index; SNS: Subjective Nutritional Score; SNS (M): Muscle component of Subjective Nutritional Score MAC: Mid Arm Circumference; MAMA: Mid Arm Muscle Area; TSF: Triceps Skinf Fold; CRP: C Reactive Protein; 6MWT inability: inability to perform the six minutes walking test; ABI: Ankle Brachial Index; High stress (disease): High degree clinical stress according with the presence of hyper-metabolic, hyper-catabolic disease.
Short term survival was analyzed by Chi-square test with correction for continuity (X2c), and long term survival by Kaplan and Meyer survival curves compared by long-rank test. OR: Odd ratio, CI: 95% confidence interval; HR: Hazard ratio.