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. Author manuscript; available in PMC: 2014 Dec 22.
Published in final edited form as: Oral Dis. 2011 Apr 26;17(8):745–752. doi: 10.1111/j.1601-0825.2011.01808.x

Figure 1.

Figure 1

A schematic comparing enzyme-linked immunoassay (ELISA) and lateral flow (LF) assays. The ELISA uses an enzyme such as horseradish peroxidase or alkaline phosphatase linked to an antibody to generate either a color change or an electrochemical signal. The ELISA requires multiple washes. The LF assay often uses visual labels such as gold nanoparticles and includes a specific capture line and a control line. The control line binds the labeled conjugate directly without a target and ensures that the sample has flowed up the LF strip