Table 6.
Length of stay end points in included studies and results for EPN, LPN and EN groups
| Outcome | Study |
Study arms |
Significance of results | |||
|---|---|---|---|---|---|---|
| EPN | LPN | EN | ||||
| ICU length of stay |
Bauer 2000 [11] |
Mean days |
16.9 ± 11.8 |
x |
17.3 ± 12.8 |
no p-value, ns |
| Doig 2013 [14] |
Mean days |
8.6 |
x |
9.3 |
RD −0.75 (−1.47 to 0.04); p = 0.06 |
|
| Heidegger 2013 [15] |
Mean days |
x |
13 |
13 |
p = 0.2592 |
|
| Cahill 2011 [12] |
Median days |
15 |
22.1 |
12.4 |
p < 0.001† |
|
| Kutsogiannis 2011 [16] |
Median days |
13.9 |
18.3 |
11.7 |
p = 0.003^ |
|
| Hospital length of stay | Bauer 2000 [11] |
Mean days |
31.2 ± 18.5 |
x |
33.7 ± 27.7 |
p = 0.0022 |
| Casaer 2011 [13] |
Median days |
16 |
14 |
x |
HR 1.06; 95% CI 1.00 to 1.13; p = 0.04. |
|
| Doig 2013 [14] |
Mean days |
25.4 |
x |
24.7 |
RD 0.7; 95% CI −1.4 to 3.1; p = 0.50 |
|
| Heidegger 2013 [15] |
Mean days |
x |
31 |
32 |
p = 0.8781 |
|
| Cahill 2011 [12] |
Median days |
47.6 |
35 |
24.8 |
p < 0.001 |
|
| Kutsogiannis 2011 [16] | Median days | 33.4 | 35.3 | 27.1 | p = 0.004 | |
EPN, early parenteral nutrition; LPN, late parenteral nutrition; EN, enteral nutrition; ICU, intensive care unit; x, not applicable; p, p-value; ns, nonsignificant; RD, risk difference; HR, hazard ratio; 95% CI, 95% confidence interval. NB: studies used different definitions for EPN, LPN and EN. †, comparing EPN versus EN and comparing LPN versus EN. ^, comparing EN versus LPN.