Table 7.
Infection end points in included studies and results for EPN, LPN and EN groups
| Outcome | Study |
Study arms |
Significance of results |
||
|---|---|---|---|---|---|
| EPN | LPN | EN | |||
| Infections (%) |
Bauer 2000 [11] |
47.0 |
x |
38.0 |
Respiratory infections: no p-value, ns |
| Bauer 2000 [11] |
18.0 |
x |
27.0 |
UTI: no p-value, ns |
|
| Casaer 2011 [13] |
26.2 |
22.8 |
x |
p = 0.008 |
|
| Doig 2013 [14] |
NR |
x |
NR |
No significant differences between standard care or EPN |
|
| Antibiotic (mean days ± SD) |
Heidegger 2013 [15] |
x |
5 ± 7 |
6 ± 7 |
p = 0.0298 |
| Antibiotic free (mean days ± SD) | Heidegger 2013 [15] | x | 15 ± 9 | 13 ± 10 | p = 0.0126† |
EPN, early parenteral nutrition; LPN, late parenteral nutrition; EN, enteral nutrition; p, p-value; ns, nonsignificant; UTI, urinary tract infections; NR, not reported; SD, standard deviation. NB: studies used different definitions for EPN, LPN and EN. †, analyses performed between day 9 and day 28.