Table 1.
Patient characteristics at baseline
| Patient characteristic | Data |
|---|---|
| Age (years) |
63.7 ± 14.2 |
| Gender [male (%)] |
16 (80) |
| APACHE II |
21.50 (18.0 to 26.0) |
| SOFA |
10.5 (9.0 to 12.0) |
| PEEP (cm H2O) |
8.0 (5.0 to 10.0) |
| FiO2 (%) |
40 (40 to 50) |
| Tidal volume (mL) |
487 ± 95.1 |
| Cstat (mL/cm H2O) |
39.2 ± 13.5 |
| PaO2/FiO2 |
206.6 ± 72.9 |
| Time of vasopressor use (h) |
25.0 (19.5 to 34.0) |
| Fluid balance (mL)a |
7,217 (6,345 to 8,545) |
| Causes of shock |
|
| Sepsis [n (%)] |
14 (70) |
| Major surgery [n (%)] |
5 (25) |
| Multiple trauma [n (%)] |
1 (5) |
| Catecholamine infusion |
|
| Norepinephrine, μg/kg/min (n = 20) |
0.33 (0.21 to 0.83) |
| Epinephrine, μg/kg/min (n = 5) |
0.26 (0.14 to 0.35) |
| Dobutamine, μg/kg/min (n = 5) |
6.0 (5.1 to 7.1) |
| Survivors (ICU) [n (%)] | 7 (35) |
APACHE II, Acute Physiology and Chronic Health Evaluation II; SOFA, Sequential Organ Failure Assessment score; PEEP, positive end-expiratory pressure; FiO2, fraction of inspired oxygen; Cstat, static respiratory compliance; PaO2, partial pressure of oxygen; ICU, intensive care unit. aFrom shock to fluid infusion. Quantitative variables are expressed as means (SD) or medians (IQR 25th to 75th percentile).