Table 2.

Factors associated with treatment interruption of ≥90 days among 757 LISA participants in British Columbia, Canada

	Unadjusted odds ratio (95% confidence interval)	p-value	Adjusted odds ratio (95% confidence interval)	p-value
Female vs. Male	2.75 (1.82–4.16)	<0.001	1.58 (0.99–2.52)	0.054
Age (per 10 year increment)	0.54 (0.43–0.68)	<0.001	0.57 (0.44–0.75)	<0.001
Current illicit drug use	1.90 (1.26–2.87)	0.002	1.68 (1.05–2.68)	0.030
Aboriginal ancestry	1.91 (1.27–2.88)	0.002
Unemployed	2.54 (1.44–4.49)	0.001	2.22 (1.16–4.23)	0.016
Completed high school	1.83 (1.23–2.72)	0.003
Unstable housing*	2.20 (1.47–3.29)	<0.001
Living situation
Alone	1.00		1.00
With many others	1.40 (0.93–2.11)	0.108	1.95 (1.22–3.14)	0.005
On the street	6.10 (2.26–16.44)	<0.001	5.08 (1.72–14.99)	0.003
Overall health self-rated (poor, fair and neutral) vs. excellent and good)	2.10 (1.41–3.13)	<0.001	1.64 (1.05–2.55)	0.030
Ever incarcerated	1.97 (1.31–2.97)	0.001
Currently earn <$15,000	2.31 (1.48–3.59)	<0.001
Food insecurity	1.76 (1.34–2.30)	0.013
Ever diagnosed with Hepatitis C**	2.58 (1.66–4.01)	<0.001
< 95% adherence in first year of treatment	3.07 (2.02–4.66)	<0.001	2.68 (1.67–4.12)	<0.001

^*Not living in a house or apartment

^**The hepatitis C variable was not considered for the final model due to collinearity with current illicit drug use