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Accumulation of exogenous cGMP in cyst inducing liquid CENBA medium by wild-type cells (grey bars), the cyclase deletion strain Δrc1_3783 (black bars), and the CRP homolog strain Δrc1_3788 (white bars). While cGMP accumulates to appreciable levels in the wild type strain, in the Δrc1_3783 and Δrc1_3788 strains levels remain <1 nM.
