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. 2014 Dec 22;9(12):e114764. doi: 10.1371/journal.pone.0114764

Table 1. Human studies with plasma levels of dietary ITCs.

Study type Subjects (n) Dose Plasma conc. (µM) Refs
Metabolisms, pharmacokinetics 4 200 µmol ITCs (largely SFN) 0.94–2.27 Ye et al., 2002 [40].
Metabolism 16 GST(+): 107 & 345.8 µmol SFN; GST(-): 95 & 342 µmol SFN 2.2; 7.3 2.3; 7.4 Gasper et al., 2005 [41].
Metabolism 4 70 or 120 µmol SFN 0.9 or 2.1 Cramer et al., 2011 [42].
Bioavailability 12 150 µmol glucoraphanin 2.2 Clarke et al., 2011 [43].
Pharmacokinetics 4 100 g watercress 0.928 (±0.25) Ji et al., 2003 [44].