Table 1. Human studies with plasma levels of dietary ITCs.
Study type | Subjects (n) | Dose | Plasma conc. (µM) | Refs |
Metabolisms, pharmacokinetics | 4 | 200 µmol ITCs (largely SFN) | 0.94–2.27 | Ye et al., 2002 [40]. |
Metabolism | 16 | GST(+): 107 & 345.8 µmol SFN; GST(-): 95 & 342 µmol SFN | 2.2; 7.3 2.3; 7.4 | Gasper et al., 2005 [41]. |
Metabolism | 4 | 70 or 120 µmol SFN | 0.9 or 2.1 | Cramer et al., 2011 [42]. |
Bioavailability | 12 | 150 µmol glucoraphanin | 2.2 | Clarke et al., 2011 [43]. |
Pharmacokinetics | 4 | 100 g watercress | 0.928 (±0.25) | Ji et al., 2003 [44]. |