Table 3. Clinical features, outcomes, laboratory and radiological findings of influenza pneumonia, compared to pneumococcal pneumonia.
No. (%) of patients | |||
Characteristics | Viral Pneumonia (Influenza) (N = 23) | Pneumococcal Pneumonia (N = 88) | P value |
Demographic data | |||
Male sex | 19 (83) | 73 (83) | >0.999 |
Agea | 71 (±10) | 69 (±11) | 0.342 |
Underlying diseases | |||
Diabetes mellitus | 8 (35) | 18 (20) | 0.161 |
Hypertension | 7 (30) | 24 (27) | 0.793 |
Chronic obstructive lung disease | 6 (26) | 31 (35) | 0.463 |
Cancer | 7 (30) | 14 (16) | 0.140 |
Ischemic heart disease | 3 (13) | 12 (14) | >0.999 |
Symptoms | |||
Fever | 17 (74) | 46 (52) | 0.097 |
Cough | 17 (74) | 51 (58) | 0.231 |
Sputum | 11 (48) | 52 (59) | 0.348 |
Rhinorrhea | 6 (26) | 6 (7) | 0.017 |
Dyspnea | 8 (35) | 46 (52) | 0.161 |
Severity and Outcomes | |||
CURB-65b | 1.7 (1, 2) | 1.5 (1, 2) | 0.981 |
PSIb | 117 (78, 136) | 104 (75, 122) | 0.286 |
Mechanical ventilation | 6 (26) | 13 (15) | 0.526 |
30-day mortality | 6 (26) | 15 (17) | 0.375 |
Laboratory findings | |||
White blood cell counts (/mm3)b | 13070 (7800, 18400) | 14410 (9425, 17275) | 0.382 |
Neuotrophil % b | 76 (70, 87) | 78 (76, 90) | 0.240 |
Lymphocyte % b | 15 (7, 21) | 11 (6, 15) | 0.081 |
C-reactive protein (mg/dL)b | 17 (8, 26) | 13 (4, 18) | 0.056 |
Serum creatinine (mg/dL)b | 1.3 (0.7, 1.5) | 1.6 (0.8, 1.7) | 0.868 |
Radiologic findings | |||
Lobar consolidation | 6 (26) | 42 (48) | 0.091 |
Centrilobular nodule | 8 (35) | 34 (39) | >0.999 |
GGO | 8 (35) | 12 (14) | 0.030 |
Continuous variables were expressed as means ± SDsa or medians (IQRs)b and were compared by the Student's t test a or Mann-Whitney U testb
CURB-65: Confusion-Urea-Respiratory-Blood pressure-65 score, PSI: Pneumonia severity index, GGO: Ground-glass opacity.