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. 2014 Dec 22;9(12):e114710. doi: 10.1371/journal.pone.0114710

Table 3. Clinical features, outcomes, laboratory and radiological findings of influenza pneumonia, compared to pneumococcal pneumonia.

No. (%) of patients
Characteristics Viral Pneumonia (Influenza) (N = 23) Pneumococcal Pneumonia (N = 88) P value
Demographic data
Male sex 19 (83) 73 (83) >0.999
Agea 71 (±10) 69 (±11) 0.342
Underlying diseases
Diabetes mellitus 8 (35) 18 (20) 0.161
Hypertension 7 (30) 24 (27) 0.793
Chronic obstructive lung disease 6 (26) 31 (35) 0.463
Cancer 7 (30) 14 (16) 0.140
Ischemic heart disease 3 (13) 12 (14) >0.999
Symptoms
Fever 17 (74) 46 (52) 0.097
Cough 17 (74) 51 (58) 0.231
Sputum 11 (48) 52 (59) 0.348
Rhinorrhea 6 (26) 6 (7) 0.017
Dyspnea 8 (35) 46 (52) 0.161
Severity and Outcomes
CURB-65b 1.7 (1, 2) 1.5 (1, 2) 0.981
PSIb 117 (78, 136) 104 (75, 122) 0.286
Mechanical ventilation 6 (26) 13 (15) 0.526
30-day mortality 6 (26) 15 (17) 0.375
Laboratory findings
White blood cell counts (/mm3)b 13070 (7800, 18400) 14410 (9425, 17275) 0.382
Neuotrophil % b 76 (70, 87) 78 (76, 90) 0.240
Lymphocyte % b 15 (7, 21) 11 (6, 15) 0.081
C-reactive protein (mg/dL)b 17 (8, 26) 13 (4, 18) 0.056
Serum creatinine (mg/dL)b 1.3 (0.7, 1.5) 1.6 (0.8, 1.7) 0.868
Radiologic findings
Lobar consolidation 6 (26) 42 (48) 0.091
Centrilobular nodule 8 (35) 34 (39) >0.999
GGO 8 (35) 12 (14) 0.030

Continuous variables were expressed as means ± SDsa or medians (IQRs)b and were compared by the Student's t test a or Mann-Whitney U testb

CURB-65: Confusion-Urea-Respiratory-Blood pressure-65 score, PSI: Pneumonia severity index, GGO: Ground-glass opacity.