Table 1. Potency of EphA4 Peptide Antagonists.
peptide | IC50 ± SE (n)a by ELISA (nM) | KD by ITC (nM) |
---|---|---|
APY | 2,700 ± 300 (9) | 1400 |
APY.am | 250 ± 20 (3) | 300 |
APY-DAla8.am | 280 ± 30 (3) | 250 |
APY-Ala8.am | 7,700 ± 400 (3) | 2500 |
APY-Aib8.am | 2,600 ± 200 (3) | ndb |
APY-βAla8.am | 31 ± 3 (13) | 30 |
n = number of experiments.
nd = not determined.