Table 1.

Results during crossover phase

Variable	N	ON state	OFF state	P-value
WVF*median (interquartile range)	20	6.4 (2.8–17.3)	9.8 (3.6–25.6)	1.000
Frequency symptom score† mean ± SD
Vomiting	21	2.38 ± 1.24	2.71 ± 1.19	0.823
Nausea	21	3.29 ± 1.06	3.48 ± 0.87	0.910
Early satiety	21	2.76 ± 1.37	2.62 ± 1.50	0.352
Bloating	21	2.33 ± 1.59	2.29 ± 1.62	0.555
Postprandial fullness	21	2.10 ± 1.26	2.38 ± 1.53	0.230
Epigastric pain	21	2.00 ± 1.38	2.33 ± 1.46	0.969
Epigastric burning	21	1.14 ± 1.42	1.38 ± 1.66	0.031
Total symptom score (TSS)	21	16.0 ± 6.29	17.19 ± 6.98	0.932
Severity symptom score‡ mean ± SD
Vomiting	21	2.10 ± 1.26	2.29 ± 1.15	0.838
Nausea	21	2.38 ± 1.12	2.71 ± 1.15	0.936
Early satiety	21	1.95 ± 1.20	1.95 ± 1.36	0.609
Bloating	21	1.71 ± 1.38	1.86 ± 1.53	0.539
Postprandial fullness	21	1.52 ± 1.03	2.00 ± 1.48	0.176
Epigastric pain	21	1.62 ± 1.28	1.90 ± 1.34	0.840
Epigastric burning	21	0.81 ± 1.08	1.10 ± 1.37	0.063
Total symptom score (TSS)	21	12.10 ± 5.83	13.81 ± 6.95	0.556

^*WVF, Weekly Vomiting Frequency.

^†For each individual symptom frequency score, 0 = absent and 4 = extremely frequent (≥7 per week), total symptom frequency score is the sum of all the individual symptom scores.

^‡For each individual symptom severity score, 0 = absent and 4 = extremely severe (requiring bed rest), total symptom severity score is the sum of all the individual symptom scores.