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. Author manuscript; available in PMC: 2014 Dec 22.
Published in final edited form as: Nature. 2013 Nov 20;503(7477):548–551. doi: 10.1038/nature12796

Extended Data Figure 3. Analysis of compound labelling rate and in vitro specificity.

Extended Data Figure 3

a, Percentage modification of K-Ras(G12C) by compounds 9 and 12 over time (n = 3, error bars denote s. d.). b, Selective single labelling of K-Ras(G12C) by compound 12 in the presence of BSA. c, Quantitative single labelling of BSA and multiple labelling of K-Ras(G12C) by DTNB. d, Comparison of modification of K-Ras(G12C) and wild-type by 12 (n = 3, error bars denote s.d.).