TABLE 2.
Molecular Mass (kDa) | Molecular Radiusa (nm) | Concentration (mg/dl) (mean ± SEM) | ||
Plasma | Lymph | |||
α1-Acid glycoprotein | 40 | 2.89 | 94.6 ± 3.0 | 38.7 ± 1.9 |
α1-Antitrypsin | 55 | 3.26 | 131.0 ± 3.9 | 49.5 ± 2.7 |
Antithrombin III | 58 | 3.33 | 5.7 ± 0.1 | 2.0 ± 0.1 |
Albumin | 66 | 3.50 | 4722 ± 64 | 1665 ± 83 |
Transferrin | 77 | 3.72 | 216.3 ± 8.4 | 75.4 ± 4.8 |
Immunoglobulin G | 150 | 4.81 | 1158 ± 40 | 215 ± 24 |
α2-Macroglobulin | 750 | 8.95 | 304 ± 35 | 34.7 ± 3.5 |
LDL | — | 10.7 | — | — |
Apo B | — | — | 82.4 ± 4.1 | 7.7 ± 0.47 |
HDL | — | 4.5 | — | — |
Apo AI | — | — | 130 ± 6.1 | 26.7 ± 1.5 |
Apo AII | — | — | 33.1 ± 1.2 | 6.8 ± 0.43 |
Complement C3 | 180 | 5.16 | 34.8 ± 1.4 | 8.3 ± 0.7 |
Molecular radii of the plasma proteins were calculated using the Stokes-Einstein equation. Lipoprotein particle radii are those obtained by NMR, and were taken from the literature, as described under Methods.