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. 2014 Dec 22;9(12):e115197. doi: 10.1371/journal.pone.0115197

Table 4. Comparison of renal function in hepatosplenic schistosomiasis patients and controls.

Hepatosplenic schistosomiasis (n = 20) Controls (n = 17) P
PUr, mg/dL 23±7.7 26±8.0 0.38
PCr, mg/dL 0.6±0.1 0.9±0.2 0.0001
GFR, mL/min/1.73 m2 130±38 103±16 0.01
Microalbuminuria, mg/day 35.8±83.6 5.5±5.3 0.12
Proteinuria, mg/day 139±148 95±61 0.26
Urinary MCP-1, pg/mg-Cr 122±134 40±28 0.01
FENa+, % 0.69±0.3 0.62±0.1 0.40
FEMg++, % 2.96±1.8 1.81±1.0 0.14
FEK+, % 0.55±0.2 0.52±0.2 0.82
TTKG 3.3±1.7 3.0±1.2 0.62
TcH2O, L/day 0.72±0.5 1.1±0.3 0.04

Values are expressed as mean ± SD. Significant P <0.05 vs. control by Student t test. PCr, plasma creatinine; PUr, plasma urea; GFR, glomerular filtration rate; MCP-1, Monocyte Chemotactic Protein-1 FENa+, fractional excretion of sodium; FEMg++, fractional excretion of magnesium; FEK+, fractional excretion of potassium; TTKG, transtubular potassium transport; TcH2O, reabsorption of free water solute.