Table 4. Comparison of renal function in hepatosplenic schistosomiasis patients and controls.
Hepatosplenic schistosomiasis (n = 20) | Controls (n = 17) | P | |
PUr, mg/dL | 23±7.7 | 26±8.0 | 0.38 |
PCr, mg/dL | 0.6±0.1 | 0.9±0.2 | 0.0001 |
GFR, mL/min/1.73 m2 | 130±38 | 103±16 | 0.01 |
Microalbuminuria, mg/day | 35.8±83.6 | 5.5±5.3 | 0.12 |
Proteinuria, mg/day | 139±148 | 95±61 | 0.26 |
Urinary MCP-1, pg/mg-Cr | 122±134 | 40±28 | 0.01 |
FENa+, % | 0.69±0.3 | 0.62±0.1 | 0.40 |
FEMg++, % | 2.96±1.8 | 1.81±1.0 | 0.14 |
FEK+, % | 0.55±0.2 | 0.52±0.2 | 0.82 |
TTKG | 3.3±1.7 | 3.0±1.2 | 0.62 |
TcH2O, L/day | 0.72±0.5 | 1.1±0.3 | 0.04 |
Values are expressed as mean ± SD. Significant P <0.05 vs. control by Student t test. PCr, plasma creatinine; PUr, plasma urea; GFR, glomerular filtration rate; MCP-1, Monocyte Chemotactic Protein-1 FENa+, fractional excretion of sodium; FEMg++, fractional excretion of magnesium; FEK+, fractional excretion of potassium; TTKG, transtubular potassium transport; TcH2O, reabsorption of free water solute.