FIG. 3.

PG is a stronger inducer of PCA in whole blood than LTA. Undiluted human whole blood was incubated with LTA or PG at the indicated concentrations (given in micrograms per milliliter) for 4 h. Subsequently, the blood was recalcified and the clotting time was determined. Values are means ± standard deviations (n = 3). Statistical analysis was performed by means of ANOVA. The overall P value was <0.0001, and P values for differences between the mean for each stimulus and the mean for the control were calculated using the standard deviation from the ANOVA model and compared to the time distribution. No adjustments for multiple tests have been used. In addition, means with the same concentrations of LTA and PG on a weight basis were compared (indicated by a line). The level of statistical significance was set at P of <0.005 (***). n.s., not significant.