Table 3.

Mouse survival following primary and secondary toxin challenges

	1° CHL^a		2° CHL

Group^b	Ricin	LT	Ricin
RiVax A	-	0/5	-

B	5/5^*	-	-

DNI A	-	5/5^*	0/5

B	0/4^c	-	-

Dual A	-	4/5	4/4^*

B	5/5	-	-

Vehicle A	-	0/5	-

B	0/5	-	-

CHL, challenge;

Each group of mice (left column) was arbitrarily divided into two subsets, A and B. The A subset received a primary challenge with LT, while the B subset (shaded) received a primary challenge with ricin. The DNI-immunized and the dual-immunized A subsets of animals that survived LT challenge received a secondary challenge with ricin;

A single mouse in this group of animals died of unknown causes prior to the animal’s second immunization.

, indicates statistical significance (p<0.05) based on the Mantel-Cox test.