FIG. 5.

Oral tolerance to OVA is induced in DO11.10 chimeras. In vitro recall responses of T cells from draining PLN of mice fed 10 mg of OVA (open circles and bars) and unfed mice immunized s.c with 10 μg of OVA in CFA (filled circles and bars) are shown. Data are represented as counts per minute in response to titrating doses of OVA in vitro (A) (P < 0.001) and as the SI at two doses of OVA (B). Cultures were set up 7 days after s.c. immunization. Data are representative of those from three experiments.