Table I.

Risk factors of local recurrence following radiofrequency ablation according to univariate analysis (abbreviated, courtesy by S. Mulier, reprinted with permission)

Risk factor for local recurrence	No. of patients included	p
Tumor size (>3/>5 cm)	1817	<0.001
Entity metastasis (vs. HCC)	4605	<0.001
Proximity to major vessel	375	<0.001
Superficial tumor site	70	<0.001
Percutaneous approach	4424	<0.001
Safety margin ≤5 mm (vs. 10 mm)	5224	<0.001
No pringle maneuvre performed	4690	<0.05
Local anesthesia/sedation	2491	<0.001
Modality of image guidance	4341	n.s.
Unexperienced interventionalist	4495	<0.001
Early years of intervention	5224	n.s.
n.s. = not significant