Table 4. Predictive performance of baseline adenoma attributes for predicting adenoma recurrence and invasive colorectal adenocarcinoma.
Any recurrent adenoma, N=537/3,300 |
ROC-AUC (P
value) |
||
---|---|---|---|
Advanced adenoma, N=354/3,300 | ICRCN=14/3,300 | ||
A. Covariates onlya | 59.4% (<0.0001) | 58.6% (<0.0001) | 65.5% (0.03) |
B. Covariates and attributesa | 69.0% (<0.0001) | 72.2% (<0.0001) | 88.3% (<0.0001) |
Net gainb | 9.6% (<0.0001) | 13.6% (<0.0001) | 22.8% (<0.0001) |
Abbreviations: ICRC, invasive colorectal cancer; ROC-AUC, receiver operating characteristic-area under the curve.
Any recurrent adenoma: any adenoma (including tubular, sessile, or flat) with or without risk attributes.
Attributes: Advanced adenoma: adenoma with ≥1 risk attributes. Risk attributes were defined at namely the number (≥3) and size (≥10 mm) of adenomas, and the presence of high-grade dysplasia or villous morphology.
Covariates include age, sex, smoking status, and family history of colorectal cancer.
Contrasted with the null model (i.e., the non-discrimination line).
Model B contrasted with Model A.