Table 3. The impact of lubiprostone on viscosity of gastric secretion collected during pentagastrin administration in patients with chronic constipation.

Viscometer share rates	Viscosity in chronic constipation Placebo therapy (mean±s.e.m.)	Viscosity in chronic constipation Lubiprostone therapy (mean±s.e.m.)	P value
2	4.59±1.20	14.96±3.00	<0.01
4	3.26±0.81	7.06±1.14	<0.01
6	2.43±0.41	5.30±0.94	<0.01
8	2.26±0.38	4.12±0.64	<0.01
10	2.11±0.35	3.43±0.47	<0.01
12	1.93±0.27	2.92±0.35	<0.01
14	1.84±0.23	3.04±0.41	<0.01
16	1.72±0.19	2.88±0.38	<0.01