TABLE 1.
List of open reading frames of P. gingivalis which were identified by DDRT-PCR as upregulated within GECs
| Locusa | Putative identification | Gene | Cellular role(s) |
|---|---|---|---|
| PG0130 | Phosphoglycerate mutase | pgm | Energy metabolism, glycolysis-gluconeogenesis |
| PG0147b,c | Hypothetical protein | ||
| PG0148c | Sigma 54-dependent transcriptional regulator | Regulatory functions, DNA interactions | |
| PG0155d | Riboflavin biosynthesis protein RibD | ribD | Biosynthesis of cofactors, prosthetic groups, and carriers: riboflavin, FMN, and FAD |
| PG0156d | Modification methylase, HemK family | Unknown function, general | |
| PG0159 | Endopeptidase PepO | pepO | Protein fate, degradation of proteins, peptides, and glycopeptides |
| PG0165 | Heat shock protein 15 | hslR | Protein synthesis, other |
| PG0212 | Precorrin-6y c5, 15-methyltransferase, putative | Biosynthesis of cofactors, prosthetic groups, and carriers: heme, porphyrin, and cobalamin | |
| PG0326 | Hypothetical protein | ||
| PG0338 | Hypothetical protein | ||
| PG0481 | 8-amino-7-oxononanoate synthase | bioF-1 | Biosynthesis of cofactors, prosthetic groups, and carriers: biotin |
| PG0525 | CTP synthase | pyrG | Purines, pyrimidines, nucleosides, and nucleotides: pyrimidine ribonucleotide biosynthesis |
| PG0534 | Hypothetical protein | ||
| PG1592 | HDIG domain protein | Energy metabolism: electron transport; hypothetical protein: domain | |
| PG1638 | Thioredoxin family protein | Energy metabolism, electron transport | |
| PG1642 | Cation-transporting ATPase, EI-E2 family, authentic frameshift | Transport and binding proteins: cations | |
| PG1683c | Conserved hypothetical protein | ||
| PG1684c | Hypothetical protein | ||
| PG1750 | Alpha-1,3/4-fucosidase, putative | Cell envelope, biosynthesis and degradation of surface polysaccharides and lipopolysaccharides | |
| PG1780 | 8-amino-7-oxononanoate synthase | bioF-3 | Biosynthesis of cofactors, prosthetic groups, and carriers: biotin |
| PG2080 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | bioA | Biosynthesis of cofactors, prosthetic groups, and carriers: biotin |
| PG2165 | Glycyl-tRNA synthetase | glyS | Protein synthesis, tRNA aminoacylation |
| PG2205 | 2-Dehydropantoate 2-reductase, putative | Biosynthesis of cofactors, prosthetic groups, and carriers: pantothenate and coenzyme A | |
| PG2206b | ABC transporter, ATP-binding protein | Transport and binding proteins, unknown substrate | |
| PG2227 | Hypothetical protein |
a
TIGR locus designation.
b
Identified from more than one clone.
c
Two loci with the consecutive numbers were identified from the same clone. The cloned fragments contained the 5′ end of one and 3′ end of the other.
d
Two loci were identified from one clone. The cloned fragment contained 5′ ends of the two loci.