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. 2004 Jul;72(7):3759–3768. doi: 10.1128/IAI.72.7.3759-3768.2004

TABLE 1.

Histological analysis of infected lungs

Time of analysis (days postinfection) Histological characteristics in mouse lungs
BALB/c DO11.10 SCID
14 Mild small lesions, lymphocytes, macrophages Mild small lesions, foamy macrophages, lymphocytes, some neutrophils Mild interstitial pneumonia
28 Mild small lesions, macrophages, lymphocytes Mild small lesions, few macrophages, interstitial pneumonia. Mild interstitial pneumonia
40 Moderate small organized lesions, macrophages, lymphocytes Moderate small macrophage lesions, plus neutrophils, scattered lymphocytes, interstitial pneumonia. Extensive disorganized lesions, macrophages and neutrophils
60 Moderate small organized lesions, foamy macrophages and lymphocytes Extensive lesions, foamy macrophages, neutrophils, scattered lymphocytes, interstitial pneumonia. Extensive lesions, macrophages and neutrophils, necrosis