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. 2014 Dec 23;4:7601. doi: 10.1038/srep07601

Figure 3. Polysaccharides preserved photoreceptor function in the rd10 retina.

Figure 3

(a), (d). Representative scotopic ERG responses to 0.01 (a) and 3 cd-s/m2 (d) light intensities from P26 rd10 mice treated with polysaccharides (red curve) or PBS (dark curve) from P14 to P25. Scotopic ERG responses from age-matched C57BL/6J (blue curve) are shown as comparisons. (b), (e). Average scotopic a- and b-wave amplitudes elicited at 0.01 cd-s/m2 (b) and 3 cd-s/m2 (e) light intensities. Since a waves of ERGs were negative, we presented a-wave amplitudes on the lower, negative axis. (g). Representative photopic ERG responses to 3 cd-s/m2 light intensity from rd10 mice at P26. (h). Averaged photopic b-wave amplitudes elicited at 3 cd-s/m2 light intensity from normal C57 BL/6J (blue), polysaccharides- (red curve) or PBS-treated (dark) rd10 mice. (c), (f), (i). Average latency time (time to peak) for scotopic ERG a- and b-waves at 0.01 cd-s/m2 (c) and 3 cd-s/m2 (f) light intensities, and for photopic ERG b-waves at 3 cd-s/m2 (i). Data are expressed as the means ± SEMs. n: number of animals in each group. ns, not significant, *: p < 0.05, ** p < 0.01.

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