Figure 6. Polysaccharides downregulated expression levels of apoptosis-related molecules.
(a–b). Western blot of IκBα, phospho-IκBα expressions in the retina of polysaccharides- and PBS-treated rd10 mice and WT mice. (c). NF-κB p65 expression in the retina of WT and polysaccharides- and PBS-treated rd10 mice by ELISA. (d). Analysis of CCL2 expression in the retina of WT and polysaccharides- and PBS-treated rd10 mice by ELISA. (e). GSH and GSSG expression in the retina of WT and polysaccharides- and PBS-treated rd10 mice by ELISA. (f–h). HIF1α (f), Caspase-3/7 (g), and BAX (h) are similarly upregulated in rd10 retinas (black bars), and downregulated following polysaccharides treatment (red bars). Results are presented as means ± SDs. N, number of retinas in each group. ns, not significant, * p < 0.05, **: p < 0.01.