TABLE 1.
Dose/mouse | No. of mice | % Mice with at least one organ posc | Urethraa
|
Bladdera
|
Epididymidesa
|
Testesa
|
||||
---|---|---|---|---|---|---|---|---|---|---|
% Pos | IFU ± 1 SD | % Pos | IFU ± 1 SD | % Pos | IFU ± 1 SD | % Pos | IFU ± 1 SD | |||
0 | 10 | 0 | 0 | <1.7b | 0 | <1.7 | 0 | <1.7 | 0 | <1.7 |
101 | 5 | 0 | 0 | <1.7 | 0 | <1.7 | 0 | <1.7 | 0 | <1.7 |
103 | 10 | 20 | 20 | 6.12 ± 6.67 | 0 | <1.7 | 10 | 0.3 ± 0.7 | 0 | <1.7 |
104 | 5 | 40 | 40 | 6.66 ± 6.95 | 40 | 2.70 ± 2.8 | 40 | 2.10 ± 2.37 | 40 | 2.18 ± 2.41 |
105 | 10 | 70 | 70 | 6.20 ± 6.46 | 60 | 3.76 ± 4.23 | 70 | 2.21 ± 2.37 | 60 | 1.48 ± 1.50 |
106 | 5 | 100 | 100 | 6.11 ± 6.25 | 80 | 5.25 ± 5.57 | 60 | 2.03 ± 2.29 | 20 | 1.60 ± 1.90 |
107 | 10 | 100 | 100 | 5.37 ± 5.65 | 70 | 6.20 ± 6.69 | 70 | 2.50 ± 2.75 | 50 | 1.34 ± 1.40 |
Mean log10 IFU recovered per organ ± 1 standard deviation.
Log10 50 = 1.7 (limit of detection).
Pos, positive.