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. Author manuscript; available in PMC: 2014 Dec 23.
Published in final edited form as: Arch Dis Child Fetal Neonatal Ed. 2014 Feb 19;99(4):F263–F268. doi: 10.1136/archdischild-2013-304179

Table 3.

Outcomes for Acidotic vs. Non-Acidotic ELBW Infants by Category of Acidosis

Cord pH Values <7 vs. ≥7 BE values <-12 vs. ≥-12
Outcome Variable Unadjusted Odds Ratio (95% CI) Adjusted Odds Ratio (95% CI)†† Unadjusted Odds Ratio (95% CI) Adjusted Odds Ratio (95% CI)††
Death/NDI 2.3 (1.5,3.6)** 2.5 (1.6,4.2)** 1.7 (1.3,2.3)** 1.5 (1.1,2.0)*
Death alone 2.1(1.4, 3.1)** 2.3 (1.5, 3.7)** 2.1 (1.6, 2.7)** 1.9 (1.4, 2.6)**
NDI alone 1.9 (1.1, 3.2)* 1.9 (1.0,3.4)* 1.1 (0.8, 1.7) 1.1 (0.7, 1.6)
Grade III/IV IVH 1.9 (1.2,3.0)* 1.7 (1.0,2.9)* 1.8 (1.3,2.4)** 1.6 (1.1,2.3)*
Seizures 1.4 (0.8, 2.6) 1.4 (0.7,2.6) 1.7 (1.2,2.5)* 1.4 (.9,2.2)
Respiratory distress 1.1 (0.4,3.6) X 1.1 (0.5,2.5) X
BPD 1.2 (0.7,2.0) 1.5 (0.8,2.7) 1.0 (0.7,1.4) 1.0 (0.7,1.5)
Proven NEC 0.7 (0.4, 1.6) 0.8 (0.4,1.8) 0.8 (0.5,1.3) 0.8 (0.5,1.3)
ROP 0.7 (0.4, 1.4) X

all values adjusted for Bayley version

††

It adjusted for GA, BW, sGa, multiple gestation, race/ethnicity, sex, ANS, center, and maternal hypertension, hemorrhage, and antenatal antibiotics

*

p < 0.05

**

p < 0.001

x unable to calculate