Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jan;21(1):36–47. doi: 10.1261/rna.045369.114

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Cheung et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

FIGURE 2. — The two different RdRPs show comparable transition mutational bias in with the (A) polymerase-driven spectra and (B) live virus spectra. (A) Mutational preference of A/Wuhan/359/95 and A/Vietnam/1203/04 polymerase complexes. (B) Mutational preference of recombinant RG-PR8×Wuhan^{PB2, PB1, PA, NP} and RG-PR8×VN1203^{PB2, PB1, PA, NP} viruses using the common HA gene as the template. The percentages (%) depict the specific nucleotide in yellow that mutate to the nucleotide in red, among the total number of nucleotide substitutions. Sequences generated from two independent experiments are pooled for the analysis.