TABLE 3.
Epitope specificity of 14 anti-LC3 IgA murine monoclonal antibodies with comparison to that of human serum IgA and IgG antilectin antibodies
| LC3 epitope (aa) | IgA monoclonal antibody(ies) (clone no.) | Specificity for human
|
|
|---|---|---|---|
| IgA | IgG | ||
| 1 (758-826) | 38, 41, 193, 244, 606, 728, 737, 854 | − | − |
| 2 (826-868) | —b | − | − |
| 3 (868-944) | 875 | + | + |
| 4 (944-987) | 580, 1152 | − | − |
| 5 (987-1070) | 676, 1059 | − | − |
| 6 (1070-1114) | 867 | − | +a |
| 7 (1114-1150) | — | + | + |
a
Epitope recognition lost 1 year after cure of ALA.
b
—, no antibodies.