TABLE 4.
Inhibition of amebic adherence to CHO cells by anti-LC3 IgA murine monoclonal antibodies
| IgA-producing hypridomasupernatant (LC3 epitope) | Inhibition of adherencea (%) |
|---|---|
| 38 (1) | 73 |
| 41 (1) | 25 |
| 193 (1) | 70 |
| 244 (1) | 29 |
| 606 (1) | 73 |
| 728 (1) | 36 |
| 737 (1) | 87 |
| 854 (1) | 76 |
| 875 (3) | 61 |
| 580 (4) | 72 |
| 1152 (4) | 3 |
| 676 (5) | 79 |
| 1059 (5) | 68 |
| 867 (6) | 28 |
| Control anti-Sendai virus IgA | 1 |
a
Percent inhibition of adherence is defined as comparison to control test medium without antibodies present. Cell supernatants from all anti-LC3 IgA monoclonal antibodies inhibited amebic adherence except 1152 (P < 0.01 compared to control anti-Sendai virus IgA).