Table 1. Dosing groups and necropsy schedule.

Pilot study
Group	Vector conc. (vg/ml)	Vector dose (vg)	Survival time
AAV2-hAADC high dose	8.3 × 1012	5.0 × 1011-6.0 × 1011	1 month (n = 2, female)
Pivotal toxicology study

Group	Vector conc. (vg/ml)	Vector dose (vg)	Survival time groups (male + female)
			1 month (n = 5)	3 months (n = 5)	9 months (n = 6)
Control	0	0	1 male	1 male	2(1 + 1)
AAV2-hAADC low dose	8.3 × 1011	5.0 × 1010	2(1 + 1)	2(1 + 1)	2(1 + 1)
AAV2-hAADC high dose	8.3 × 1012	5.0 × 1011	2(1 + 1)	2(1 + 1)	2(1 + 1)

Conc., concentration; vg, vector genome.