Table 1.
Sample characteristics.
| Variable | Not depressed (n = 230) |
Depressed (n = 29) |
P value† |
|---|---|---|---|
| Female, n (%) | 70 (30.4%) | 14 (48.3%) | 0.085 |
| Age, mean (SD) | 62.7 (7.5) | 60.0 (8.3) | 0.057 |
| BMI, mean (SD) | 26.4 (6.1) | 26.1 (5.9) | 0.808 |
| Comorbidities, mean (SD) | 2.4 (2.2) | 3.1 (1.6) | 0.061 |
| Diabetes mellitus, n (%) | 32 (13.9%) | 1 (3.4%) | 0.195 |
| OSA, n (%) | 21 (9.1%) | 5 (17.2%) | 0.298 |
| Arterial hypertension, n (%) | 109 (47.4%) | 15 (51.7%) | 0.808 |
| Malignancy, n (%) | 27 (11.7%) | 3 (10.3%) | 0.931 |
| GOLD stage, n (%)†† | |||
| I | 17 (7.4%) | 2 (6.9%) | 0.035 |
| II | 74 (32.2%) | 16 (55.2%) | |
| III | 87 (37.8%) | 10 (34.5%) | |
| IV | 52 (22.6%) | 1 (3.5%) | |
| CAT, mean (SD) | 15.7 (7.1) | 17.4 (7.4) | 0.213 |
| BODE index, mean (SD) | 3.4 (2.4) | 2.8 (2.3) | 0.203 |
| MRC-dyspnoea, mean (SD) | 1.7 (1.1) | 1.8 (1.0) | 0.736 |
| FEV1%, mean (SD) | 46.6 (20.7) | 54.5 (21.2) | 0.044 |
| 6-MWT (meters), mean (SD) | 412 (131) | 410 (124) | 0.916 |
†Frequencies and means were compared using χ 2-tests and independent t-tests, respectively.
†† χ 2-test for the frequency distribution across GOLD stages I/II/III/IV in depressed versus nondepressed patients.
6-MWT: 6-minute walking test; BMI: body mass index; CAT: chronic obstructive pulmonary disease assessment test; CPAP: continuous positive airway pressure; FEV1%: percentage of predicted forced expiratory volume in one second; GOLD: global initiative for chronic obstructive pulmonary disease; MRC-dyspnoea: Medical Research Council dyspnoea scale; OSA: obstructive sleep apnoea.