Table 2.

The IC₅₀ concentration of the quinazolinone-based compounds against MCF-7, MCF-10, and WRL-68 cell lines after 24, 48, and 72 h.

Compound	Cell line	Classification	IC50 (μg/mL)
			24 h	48 h	72 h
(1)	MCF-7	Breast cancer cells	8.063 × 10−6 mol/L	7.599 × 10−6 mol/L	6.246 × 10−6 mol/L
	MCF-10	Normal breast cells	0.483 × 10−6 mol/L	0.483 × 10−6 mol/L	0.483 × 10−6 mol/L
	WRL-68	Normal hepatic cells	0.773 × 10−6 mol/L	0.773 × 10−6 mol/L	0.773 × 10−6 mol/L
(2)	MCF-7	Breast cancer cells	7.609 × 10−6 mol/L	6.621 × 10−6 mol/L	5.910 × 10−6 mol/L
	MCF-10	Normal breast cells	0.483 × 10−6 mol/L	0.483 × 10−6 mol/L	0.483 × 10−6 mol/L
	WRL-68	Normal hepatic cells	0.773 × 10−6 mol/L	0.773 × 10−6 mol/L	0.773 × 10−6 mol/L
Doxorubicin	MCF-7	Breast cancer cells	4.471 × 10−6 mol/L	4.195 × 10−6 mol/L	3.827 × 10−6 mol/L