Table 2.

Model parameters.

Symbol	Description	Value (slow/fast)	References
c10	1st Mooney-Rivlin parameter (fitted)	6.352e−10 kPa	[A]
c01	2nd Mooney-Rivlin parameter (fitted)	3.627 kPa	[A]
b1	1st anisotropy parameter (fitted)	2.756e−5 kPa	[B]
d1	2nd anisotropy parameter (fitted)	43.373 [–]	[B]
Pmax	max. isometric stress	73.0 kPa	[B]
fs	stimulation frequency	single twitch, 50 Hz, 100 Hz	[C]
x0	average distortion induced through the power stroke	0.05 μm	[C]
f′	XB-detachment rate (from A1)	5/15 ms−1	[C]
h0	power stroke forward rate	0.08/0.24 ms−1	[C]
h′	power stroke backward rate	0.06/0.18 ms−1	[C]
f	XB-attachment rate of an isometric contraction	0.5/1.5 ms−1	[C]
g	XB-detachment rate if no neighbor is in the A2 state	0.04/0.12 ms−1	[C]
Ttot	number of possible XB connections at ℓS	140 μM	[C]
ν	influence of cooperative effects (fitted)	3.0/3.4 [–]	[D]
ϑ	level of distortion dependence (fitted)	1700/1000 [–]	[D]
ℓ0S	resting sarcomere length	2.0 μm	[E]
ℓoptS	optimal sarcomere length	2.4 μm	[F]
Cm	membrane capacitance	0.58/1.0 μF/cm2	[C]
Am	surface-area-to-volume ratio	500 cm−1	[G]
σ	conductivity	3.828 mS/cm	[G]

References, [A] – Zheng et al. (1999); [B] – Hawkins and Bey (1994); [C] – Shorten et al. (2007); [D] – Ranatunga (1984); [E] – Edman (1979); [F] – Burkholder and Lieber (2001); [G] – Röhrle et al. (2012). The table also indicates which parameters were obtained through fitting.