Fig. 3.
Effect of HFS on the perception of mechanical punctate stimuli (delivered to the distal and proximal area relative to the site of HFS; A) and thermal laser stimuli selectively activating C fibers (B). Group-level means ± SD of the intensity of perception [numerical rating scale (NRS) scores] obtained at the 3 different time points: before HFS (T0), 20 min after HFS (T1), and 45 min after HFS (T2). Note that HFS significantly enhanced the perception of mechanical punctate and thermal stimuli at both T1 and T2. *P < 0.05, statistical significance of post hoc tests.