(A–F). Real time RT-PCR at 48 hours after bacterial challenge. mRNA levels of IL-1β, IL-α, IL-6, TNF- α, CINC-1 (rat IL-8) and MMP-9 were significantly elevated in the infected low Dk wearing corneas when compared with levels in the uninfected low (or high) Dk wearing corneas. mRNA levels in the latter two appeared similar to the non-lens wearing, normal cornea.