Table 4.
Chemotherapy and Radiation (CR) (n=1729) |
Preoperative Chemotherapy and Radiation (Trimodality) (n=1729) |
P value |
|
---|---|---|---|
Age (years) | 61.9 ± 9.9 | 61.7 ± 9.4 | .686 |
Male Gender | 921 (53.3%) | 886 (51.2%) | .247 |
Caucasian | 1527 (88.3%) | 1534 (88.7%) | .749 |
Urban Location | 1232 (71.3%) | 1212 (70.1%) | .478 |
Income >$35000/year | 1241 (71.8%) | 1232 (71.3%) | .763 |
Charlson/Deyo Score | 0 1170 (67.7%) 1 459 (26.5%) 2 100 (5.8%) |
0 1164(67.3%) 1 455 (26.3%) 2 110 (6.4%) |
.775 |
Distance traveled for treatment (miles) | 78.0 ± 716.0 | 115.3 ± 902.0 | .178 |
Tumor Size (mm) | 44.9 ± 24.7 | 44.9 ± 31.6 | .996 |
Facility Reporting Case | Community Cancer Program: 189 (10.9%) Comprehensive Community Cancer Program: 904 (52.3%) Academic/Research Program: 636 (36.8%) |
Community Cancer Program: 213 (12.3%) Comprehensive Community Cancer Program: 896 (51.8%) Academic/Research Program: 620 (35.9%) |
.433 |
Chemotherapy Type | Single agent: 98 (6.2%) Multiagent: 1487 (93.8%) |
Single agent: 61 (4.0%) Multiagent: 1477 (96.0%) |
|
Chemotherapy-Surgery Sequence (available n=1729) | Before surgery: 1448 (83.7%) Before and after surgery: 281 (16.3%) |
||
Cumulative radiation dose (cGy) | 6263.4 ± 3798.9 (6.1% Missing) | 5279.0± 2606.8 (9.8% Missing) | <.001 |
Cumulative radiation dose (cGy) (n=1560) | ≤3500: 25 (1.6%) 3501–4500: 561 (36.0%) >4500: 974 (62.4%) |
||
Cumulative radiation dose (cGy) (n=1625) | ≤4000: 156 (9.6%) 4001–5000: 110 (6.8%) 5001–6000: 317 (19.5%) >6000: 1042 (64.1%) |
||
Radiation-Surgery Sequence | Radiation before surgery: 1674 (96.8%) Radiation before and after surgery: 55 (3.2%) |
||
Type of operation | Lobectomy: 1372 (79.4%) Pneumonectomy: 257 (14.9%) Other: 100 (5.8%) |
||
Median Survival (months) | 19.7 ± 0.6 | 35.9 ± 1.6 | <.001 |