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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: J Thorac Oncol. 2014 May;9(5):612–621. doi: 10.1097/JTO.0000000000000152

Table 4.

Baseline characteristics, treatment-related variables, and long-term outcomes in propensity score matched patients with clinical stage IIIA NSCLC who received combination therapy with chemotherapy and radiation versus those who received trimodality therapy. The CR group refers to patients who received chemotherapy and radiation in any sequence. The trimodality group refers to patients who underwent preoperative chemotherapy and radiation therapy.

Chemotherapy and
Radiation (CR) (n=1729)		 Preoperative Chemotherapy
and Radiation (Trimodality)
(n=1729)		 P
value
Age (years) 61.9 ± 9.9 61.7 ± 9.4 .686
Male Gender 921 (53.3%) 886 (51.2%) .247
Caucasian 1527 (88.3%) 1534 (88.7%) .749
Urban Location 1232 (71.3%) 1212 (70.1%) .478
Income >$35000/year 1241 (71.8%) 1232 (71.3%) .763
Charlson/Deyo Score 0  1170 (67.7%)
1  459 (26.5%)
2  100 (5.8%)		 0  1164(67.3%)
1  455 (26.3%)
2  110 (6.4%)		 .775
Distance traveled for treatment (miles) 78.0 ± 716.0 115.3 ± 902.0 .178
Tumor Size (mm) 44.9 ± 24.7 44.9 ± 31.6 .996
Facility Reporting Case Community Cancer Program: 189 (10.9%)
Comprehensive Community Cancer Program: 904 (52.3%)
Academic/Research Program: 636 (36.8%)		 Community Cancer Program: 213 (12.3%)
Comprehensive Community Cancer Program: 896 (51.8%)
Academic/Research Program: 620 (35.9%)		 .433
Chemotherapy Type Single agent: 98 (6.2%)
Multiagent: 1487 (93.8%)		 Single agent: 61 (4.0%)
Multiagent: 1477 (96.0%)
Chemotherapy-Surgery Sequence (available n=1729) Before surgery: 1448 (83.7%)
Before and after surgery: 281 (16.3%)
Cumulative radiation dose (cGy) 6263.4 ± 3798.9 (6.1% Missing) 5279.0± 2606.8 (9.8% Missing) <.001
Cumulative radiation dose (cGy) (n=1560) ≤3500: 25 (1.6%)
3501–4500: 561 (36.0%)
>4500: 974 (62.4%)
Cumulative radiation dose (cGy) (n=1625) ≤4000: 156 (9.6%)
4001–5000: 110 (6.8%)
5001–6000: 317 (19.5%)
>6000: 1042 (64.1%)
Radiation-Surgery Sequence Radiation before surgery: 1674 (96.8%)
Radiation before and after surgery: 55 (3.2%)
Type of operation Lobectomy: 1372 (79.4%)
Pneumonectomy: 257 (14.9%)
Other: 100 (5.8%)
Median Survival (months) 19.7 ± 0.6 35.9 ± 1.6 <.001