Table 5.
Simulation result on estimation of recombination rate between three markers on two chromosome with known order, linkage phases, and r value
Marker | Segregation type | True value of r | Linkage phase | r̂ | LOD score |
|
||
---|---|---|---|---|---|---|---|---|
M1 | M2 | ab×cd | 0.100 | c×c | 0.125 | 54.960 | 0.112 ± 0.005 | |
r×r | 0.500 | 54.960 | ||||||
c×r | 0.500 | 0.000 | ||||||
r×c | 0.500 | 0.000 | ||||||
| ||||||||
M1 | M3 | ab×cd | 0.500 | c×c | 0.500 | 0.590 | 0.500±0.000 | |
r×r | 0.423 | 0.590 | ||||||
c×r | 0.500 | 0.054 | ||||||
r×c | 0.488 | 0.054 | ||||||
| ||||||||
M2 | M3 | ab×cd | 0.500 | c×c | 0.500 | 0.048 | 0.500±0.000 | |
r×r | 0.465 | 0.048 | ||||||
c×r | 0.483 | 0.326 | ||||||
r×c | 0.500 | 0.326 |
r: Recombination rate; r̂: Estimate of r; : The average of 100 estimate of r.
c: Coupling in the paternal parent and uninformative in the maternal parent, or vice versa; r: Repulsion in the paternal parent and uninformative in the maternal parent, or vice versa; c×c: Coupling in both parents; r×r: Repulsion in both parents; c×r or r×c: Coupling in the maternal parent and repulsion in the paternal parent, or vice versa.