Table 1.

Examples of valuable fatty acid-derived chemicals produced by metabolically engineered microorganisms.

Chemical	Organism	Titer	Reference
FAMEs (C12–18)	E. coli	16 mg/L	Nawabi et al. (2011)
FAEEs (C12–20)	E. coli	1.5 g/L	Zhang et al. (2012a)
	S. cerevisiae	47.6 mg/L	Shi et al. (2014)
FASEs (C12–18)	E. coli	1.05 g/L	Guo et al. (2014)
Butanol	E. coli	0.81 mg/L	Mattam and Yazdani (2013)
	E. coli	30 g/L	Shen et al. (2011)
	S. cerevisiae	2.5 mg/L	Steen et al. (2008)
	S. cerevisiae	242.8 mg/L	Si et al. (2014)
	C. saccharoperbutylacetonicum	32.8 g/L	Richter et al. (2012)
3-Methyl-1-pentanol	E. coli	384.3 mg/L	Zhang et al. (2008)
Fatty alcohols (C4–5)	E. coli	4035 mg/L	Huo et al. (2011)
Fatty alcohols (C6–10)	E. coli	0.33 g/L	Dellomonaco et al. (2011)
Fatty alcohols (C12, C14)	E. coli	0.45 g/L	Zheng et al. (2012)
Fatty alcohols (C12–18)	E. coli	1.725 g/L	Liu et al. (2013)
Fatty alcohols (C16–18)	E. coli	0.1 g/L	Zheng et al. (2012)
	S. cerevisiae	0.1 g/L	Runguphan and Keasling (2014)
Pentane	Y. lipolytica	4.98 mg/L	Blazeck et al. (2013)
Alkanes	E. coli	580.8 mg/L	Choi and Lee (2013)
Iso-alkanes	E. coli	5 mg/L	Howard et al. (2013)
Alkanes/Alkenes	E. coli	300 mg/L	Schirmer et al. (2010)
Alkenes	E. coli	97.6 mg/L	Liu et al. (2014)
Long-chain alkenes	E. coli	40 μg/L	Beller et al. (2010)
Hydroxy fatty acid (C18)	S. pombe	137 μg/L	Holic et al. (2012)
Hydroxy fatty acid (C18)	Y. lipolytica	60 mg/g DCW	Beopoulos et al. (2014)
Hydroxy fatty acid (C14)	C. tropicalis	174 g/L	Lu et al. (2010)
ω-1-Hydroxy fatty acid	B. pumilus	570 mg/L	Dellomonaco et al. (2011)
Dicarboxylic acid (C14)	C. tropicalis	210 g/L	Picataggio et al. (1992)
Methyl ketone	E. coli	500 mg/L	Park et al. (2012)
Lactone	Y. lipolytica	11 g/L	Wache et al. (2003)
ω-3-eicosapentaenoic acid (EPA)	Y. lipolytica	0.15 g/g DCW	Xue et al. (2013)
Triacylglyceride (TAG)	E. coli	1.1 mg/L	Rucker et al. (2013)
Poly-3-hydroxylalkanoates (mcl-PHA)	E. coli	0.4 g/L	Wang et al. (2012)
Medium-chain fatty acids (MCFAs)	E. coli	263 mg/L	Torella et al. (2013)

DCW, dry cell weight.