Table 2.
MicroRNA dysregulation associated with reovirus infection
| MicroRNA | Mean control |
Mean reovirus infected |
Fold change control vs reovirus |
|---|---|---|---|
| hsa-miR-520g | 1 | 160.7085065 | −160.7085065 |
| hsa-miR-516a-3p | 1 | 107.3253392 | −107.3253392 |
| hsa-miR-218 | 1 | 97.48225048 | −97.48225048 |
| hsa-miR-548h | 1 | 94.49078931 | −94.49078931 |
| hsa-miR-200b | 1 | 86.57758264 | −86.57758264 |
| hsa-miR-487a | 1 | 84.05077481 | −84.05077481 |
| hsa-miR-1266 | 1 | 63.48320414 | −63.48320414 |
| hsa-miR-571 | 1 | 51.94547276 | −51.94547276 |
| hsa-miR-33b | 1 | 51.94547276 | −51.94547276 |
| hsa-miR-620 | 1 | 50.66350261 | −50.66350261 |
| hsa-miR-138 | 1 | 50.17635193 | −50.17635193 |
| hsa-miR-410 | 1 | 48.9975499 | −48.9975499 |
| hsa-miR-656 | 1 | 47.81874787 | −47.81874787 |
| hsa-miR-339-5p | 1 | 47.81874787 | −47.81874787 |
| hsa-miR-519e | 1 | 46.63994584 | −46.63994584 |
| hsa-miR-1308 | 51.56146402 | 1 | 51.56146402 |
| hsa-miR-296-5p | 53.86708094 | 1 | 53.86708094 |
| hsa-miR-187 | 55.51959193 | 1 | 55.51959193 |
| hsa-miR-30e | 57.69091082 | 1 | 57.69091082 |
| hsa-miR-582-5p | 65.02048101 | 1 | 65.02048101 |
| hsa-miR-9 | 74.1055701 | 1 | 74.1055701 |
| hsa-miR-374b | 78.79269762 | 1 | 78.79269762 |
| hsa-miR-23a | 83.23959837 | 1 | 83.23959837 |
| hsa-miR-34a | 91.46539779 | 1 | 91.46539779 |
| hsa-miR-93 | 93.29197913 | 1 | 93.29197913 |
| hsa-miR-363 | 106.2343414 | 1 | 106.2343414 |
| hsa-miR-15b | 116.5409176 | 1 | 116.5409176 |
| hsa-miR-186 | 117.6316242 | 1 | 117.6316242 |
| hsa-miR-374a | 199.5630123 | 1 | 199.5630123 |
| hsa-let-7d | 240.5104802 | 1 | 240.5104802 |
The cell line SK-Mel28 was exposed to reovirus in suspension. The chart depicts the 15 microRNAs that were most increased in response to reovirus infection (top) and the 15 microRNAs that were most decreased (bottom); note that microRNA-let-7d was the most downregulated of all the over 600 microRNAs that were tested.